Mexiletine hydrochloride
Mexiletine, Namuscla (mexiletine hydrochloride) is a small molecule pharmaceutical. Mexiletine hydrochloride was first approved as Mexitil on 1985-12-30. It is used to treat cardiac arrhythmias, diabetic neuropathies, ventricular fibrillation, and ventricular premature complexes in the USA. It has been approved in Europe to treat myotonic disorders.
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Brand Name | Status | Last Update |
|---|---|---|
| mexiletine hcl | 2008-04-29 | |
| mexiletine hydrochloride | ANDA | 2025-02-05 |
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32 clinical trials
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Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | — | — | 1 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | — | — | — | 1 |
| Peripheral nervous system diseases | D010523 | — | G64 | — | 1 | — | — | — | 1 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | — | 1 | — | — | — | 1 |
| Communicable diseases | D003141 | — | — | — | 1 | — | — | — | 1 |
| Nervous system diseases | D009422 | — | G00-G99 | — | 1 | — | — | — | 1 |
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Drug
General
| Drug common name | Mexiletine hydrochloride |
| INN | mexiletine |
| Description | Mexiletine is an aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol. It has a role as an anti-arrhythmia drug. It is an aromatic ether and a primary amino compound. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cccc(C)c1OCC(C)N.Cl |
Identifiers
| PDB | — |
| CAS-ID | 5370-01-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1200606 |
| ChEBI ID | 6917 |
| PubChem CID | 4178 |
| DrugBank | DB00379 |
| UNII ID | 1U511HHV4Z (ChemIDplus, GSRS) |
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816 adverse events reported
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